UAntwerp – Faculty of Pharmaceutical, Biomedical and Veterinary Sciences
Blog Faculty of Pharmaceutical, Biomedical and Veterinary Sciences
Recent research by Prof. Guy Caljon and Dr. Laura Dirkx found that Leishmania parasites can enter a dormant state in bone marrow stem cells, making them resistant to drugs. This highlights the need for new treatments to target this phase and improve leishmaniasis management.
Leishmaniasis is a neglected tropical parasitic disease caused by Leishmania species that are transmitted by the bites of female sand flies. The failure rate of leishmaniasis treatment is rising in recent years due to the emergence of resistance to the major antileishmanial drugs. Evaluating the impact of drug resistance on parasite fitness is pivotal for monitoring its development and spread.